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Overexpression of miR-21-5p promotes proliferation and invasion of colon adenocarcinoma cells through targeting CHL1
BACKGROUND: This study aims to investigate the effect of miR-21-5p on process of colon adenocarcinoma (COAD) cells and its connection with neural cell adhesion molecule L1 (CHL1). METHODS: Different expressions of mRNAs and miRNAs were calculated with microarray analysis. QRT-PCR and western blot we...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048725/ https://www.ncbi.nlm.nih.gov/pubmed/30134821 http://dx.doi.org/10.1186/s10020-018-0034-5 |