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Overexpression of miR-21-5p promotes proliferation and invasion of colon adenocarcinoma cells through targeting CHL1

BACKGROUND: This study aims to investigate the effect of miR-21-5p on process of colon adenocarcinoma (COAD) cells and its connection with neural cell adhesion molecule L1 (CHL1). METHODS: Different expressions of mRNAs and miRNAs were calculated with microarray analysis. QRT-PCR and western blot we...

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Detalles Bibliográficos
Autores principales:	Yu, Weihua, Zhu, Kongxi, Wang, Yulong, Yu, Hualong, Guo, Jianqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048725/ https://www.ncbi.nlm.nih.gov/pubmed/30134821 http://dx.doi.org/10.1186/s10020-018-0034-5

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