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Determination of the binding affinities of Neisseria meningitidis serogroup W capsule polymerase with two nucleotide sugar substrates

OBJECTIVE: Meningococcal meningitis is a public health burden. Immunization strategies have reduced global incidence of the disease. Glycoconjugate vaccines are the most effective type of vaccine to combat most causes of meningococcal meningitis. These vaccines contain capsular polysaccharide fragme...

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Detalles Bibliográficos
Autores principales: Sharyan, Abeer, Gonzalez, Cendy, Ukaegbu, Ophelia, Powell, Kayla, McCarthy, Pumtiwitt C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048754/
https://www.ncbi.nlm.nih.gov/pubmed/30012207
http://dx.doi.org/10.1186/s13104-018-3596-y