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CD133+ cells derived from skeletal muscles of Duchenne muscular dystrophy patients have a compromised myogenic and muscle regenerative capability

Cell-mediated gene therapy is a possible means to treat muscular dystrophies like Duchenne muscular dystrophy. Autologous patient stem cells can be genetically-corrected and transplanted back into the patient, without causing immunorejection problems. Regenerated muscle fibres derived from these cel...

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Detalles Bibliográficos
Autores principales: Meng, Jinhong, Muntoni, Francesco, Morgan, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048760/
https://www.ncbi.nlm.nih.gov/pubmed/29783100
http://dx.doi.org/10.1016/j.scr.2018.05.004