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Curcumin derivative, 2,6-bis(2-fluorobenzylidene)cyclohexanone (MS65) inhibits interleukin-6 production through suppression of NF-κB and MAPK pathways in histamine-induced human keratinocytes cell (HaCaT)

BACKGROUND: Histamine is a well-known mediator involved in skin allergic responses through up-regulation of pro-inflammatory cytokines. Antihistamines remain the mainstay of allergy treatment, but they were found limited in efficacy and associated with several common side effects. Therefore, alterna...

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Detalles Bibliográficos
Autores principales: Razali, Nurul Atika, Nazarudin, Nur Amiza, Lai, Kok Song, Abas, Faridah, Ahmad, Syahida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048808/
https://www.ncbi.nlm.nih.gov/pubmed/30012134
http://dx.doi.org/10.1186/s12906-018-2223-8