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Phosphonate coating of SiO(2) nanoparticles abrogates inflammatory effects and local changes of the lipid composition in the rat lung: a complementary bioimaging study

BACKGROUND: The well-known inflammatory and fibrogenic changes of the lung upon crystalline silica are accompanied by early changes of the phospholipid composition (PLC) as detected in broncho-alveolar lavage fluid (BALF). Amorphous silica nanoparticles (NPs) evoke transient lung inflammation, but t...

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Detalles Bibliográficos
Autores principales: Großgarten, Mandy, Holzlechner, Matthias, Vennemann, Antje, Balbekova, Anna, Wieland, Karin, Sperling, Michael, Lendl, Bernhard, Marchetti-Deschmann, Martina, Karst, Uwe, Wiemann, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048815/
https://www.ncbi.nlm.nih.gov/pubmed/30012173
http://dx.doi.org/10.1186/s12989-018-0267-z