CXCR4 and its ligand CXCL12 display opposite expression profiles in feline mammary metastatic disease, with the exception of HER2-overexpressing tumors

BACKGROUND: The receptor CXCR4 and its ligand CXCL12 play crucial roles in breast cancer. Despite the fact that the spontaneous feline mammary carcinoma (FMC) is considered a suitable model for breast cancer studies, the importance of the CXCR4/CXCL12 axis in FMC is completely unknown. Therefore, th...

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Detalles Bibliográficos
Autores principales: Marques, Cláudia S., Santos, Ana Rita, Gameiro, Andreia, Correia, Jorge, Ferreira, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048851/
https://www.ncbi.nlm.nih.gov/pubmed/30012106
http://dx.doi.org/10.1186/s12885-018-4650-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048851/
https://www.ncbi.nlm.nih.gov/pubmed/30012106
http://dx.doi.org/10.1186/s12885-018-4650-9

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