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miR-589 promotes gastric cancer aggressiveness by a LIFR-PI3K/AKT-c-Jun regulatory feedback loop

BACKGROUND: As novel biomarkers for various cancers, microRNAs negatively regulate genes expression via promoting mRNA degradation and suppressing mRNA translation. miR-589 has been reported to be deregulated in several human cancer types. However, its biological role has not been functionally chara...

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Detalles Bibliográficos
Autores principales: Zhang, Feifei, Li, Kaitao, Pan, Mingxin, Li, Weidong, Wu, Juan, Li, Mingyi, Zhao, Liang, Wang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048856/
https://www.ncbi.nlm.nih.gov/pubmed/30012200
http://dx.doi.org/10.1186/s13046-018-0821-4