An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

BACKGROUND: Myelin oligodendrocyte glycoprotein (MOG)-reactive T-helper (Th)1 cells induce conventional experimental autoimmune encephalomyelitis (cEAE), characterized by ascending paralysis and monocyte-predominant spinal cord infiltrates, in C57BL/6 wildtype (WT) hosts. The same T cells induce an...

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Detalles Bibliográficos
Autores principales: Stoolman, Joshua S., Duncker, Patrick C., Huber, Amanda K., Giles, David A., Washnock-Schmid, Jesse M., Soulika, Athena M., Segal, Benjamin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048869/
https://www.ncbi.nlm.nih.gov/pubmed/30012158
http://dx.doi.org/10.1186/s12974-018-1237-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048869/
https://www.ncbi.nlm.nih.gov/pubmed/30012158
http://dx.doi.org/10.1186/s12974-018-1237-y

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