Cargando…

An IFNγ/CXCL2 regulatory pathway determines lesion localization during EAE

BACKGROUND: Myelin oligodendrocyte glycoprotein (MOG)-reactive T-helper (Th)1 cells induce conventional experimental autoimmune encephalomyelitis (cEAE), characterized by ascending paralysis and monocyte-predominant spinal cord infiltrates, in C57BL/6 wildtype (WT) hosts. The same T cells induce an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stoolman, Joshua S., Duncker, Patrick C., Huber, Amanda K., Giles, David A., Washnock-Schmid, Jesse M., Soulika, Athena M., Segal, Benjamin M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048869/ https://www.ncbi.nlm.nih.gov/pubmed/30012158 http://dx.doi.org/10.1186/s12974-018-1237-y

Ejemplares similares

Regional CNS responses to IFN-γ determine lesion localization patterns during EAE pathogenesis
por: Lees, Jason R., et al.
Publicado: (2008)

Neutrophil-related factors as biomarkers in EAE and MS
por: Rumble, Julie M., et al.
Publicado: (2015)

IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci
por: Lee, Eunyoung, et al.
Publicado: (2012)

Erratum to: IFN-gamma signaling in the central nervous system controls the course of experimental autoimmune encephalomyelitis independently of the localization and composition of inflammatory foci
por: Lee, Eunyoung, et al.
Publicado: (2016)

SLC/CCL21-mediated anti-tumor responses require IFNγ, MIG/CXCL9 and IP-10/CXCL10
por: Sharma, Sherven, et al.
Publicado: (2003)

ESAT6-Induced IFNγ and CXCL9 Can Differentiate Severity of Tuberculosis
por: Hasan, Zahra, et al.
Publicado: (2009)

High levels of interferon-gamma (IFNγ) in macrophage activation syndrome (MAS) and CXCL9 levels as a biomarker for IFNγ production in MAS
por: Bracaglia, C, et al.
Publicado: (2015)

Plasmacytoid Dendritic Cells Depletion and Elevation of IFN-γ Dependent Chemokines CXCL9 and CXCL10 in Children With Multisystem Inflammatory Syndrome
por: Caldarale, Francesca, et al.
Publicado: (2021)

Synergistic Up-Regulation of CXCL10 by Virus and IFN γ in Human Airway Epithelial Cells
por: Oslund, Karen L., et al.
Publicado: (2014)

Regulatory Lymphocytes Are Key Factors in MHC-Independent Resistance to EAE
por: Marín, Nieves, et al.
Publicado: (2014)

The Dynamics of the Skin’s Immune System
por: Nguyen, Alan V., et al.
Publicado: (2019)

Neuroantigen-Specific CD4 Cells Expressing Interferon-γ (IFN-γ), Interleukin (IL)-2 and IL-3 in a Mutually Exclusive Manner Prevail in Experimental Allergic Encephalomyelitis (EAE)
por: Karulin, Alexey Y., et al.
Publicado: (2012)

HIV-1 Tat Co-Operates with IFN-γ and TNF-α to Increase CXCL10 in Human Astrocytes
por: Williams, Rachel, et al.
Publicado: (2009)

IFN-γ production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo
por: Sawitzki, Birgit, et al.
Publicado: (2005)

RTL551 Treatment of EAE Reduces CD226 and T-bet+ CD4 T Cells in Periphery and Prevents Infiltration of T-bet+ IL-17, IFN-γ Producing T Cells into CNS
por: Sinha, Sushmita, et al.
Publicado: (2011)

Deletion of astroglial CXCL10 delays clinical onset but does not affect progressive axon loss in a murine autoimmune multiple sclerosis model
por: Mills Ko, Emily, et al.
Publicado: (2014)

Induction of gut regulatory CD39(+) T cells by teriflunomide protects against EAE
por: Ochoa-Repáraz, Javier, et al.
Publicado: (2016)

Endogenous adaptation to low oxygen modulates T-cell regulatory pathways in EAE
por: Esen, Nilufer, et al.
Publicado: (2016)

A TLR–CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice
por: Zhang, Jing, et al.
Publicado: (2019)

Autocrine IFNγ Controls the Regulatory Function of Lymphoproliferative Double Negative T Cells
por: Juvet, Stephen C., et al.
Publicado: (2012)

Heterodimeric IL-15 delays tumor growth and promotes intratumoral CTL and dendritic cell accumulation by a cytokine network involving XCL1, IFN-γ, CXCL9 and CXCL10
por: Bergamaschi, Cristina, et al.
Publicado: (2020)

CXCL16-positive dendritic cells enhance invariant natural killer T cell-dependent IFNγ production and tumor control
por: Veinotte, Linnea, et al.
Publicado: (2016)

Rethinking EAE pathogenesis
por: Van Epps, Heather L.
Publicado: (2005)

PARing down EAE
por: Van Epps, Heather L.
Publicado: (2006)

Modulation of Ryanodine Receptors Activity Alters the Course of Experimental Autoimmune Encephalomyelitis in Mice
por: Osipchuk, Natalia C., et al.
Publicado: (2021)

Lack of Association between IFN-γ, CXCL10 and TGF-β1 Gene Polymorphisms and Liver Complication in HIV-infected Thais
por: Akekawatchai, Chareeporn, et al.
Publicado: (2022)

Blockade Effects of Anti-Interferon- (IFN-) γ Autoantibodies on IFN-γ-Regulated Antimicrobial Immunity
por: Krisnawati, Dyah Ika, et al.
Publicado: (2019)

Elevated serum IFN-γand IFN-γ/IL-6 ratio in Kikuchi-Fujimoto disease
por: He, Tingyan, et al.
Publicado: (2023)

IFNα and IFNγ Impede Marek’s Disease Progression
por: Bertzbach, Luca D., et al.
Publicado: (2019)

IFN-γ Mediates the Rejection of Haematopoietic Stem Cells in IFN-γR1-Deficient Hosts
por: Rottman, Martin, et al.
Publicado: (2008)

IFN-γ modulates Ly-49 receptors on NK cells in IFN-γ-induced pregnancy failure
por: Li, Zhong-Yin, et al.
Publicado: (2015)

Targeting Signaling Pathway Downstream of RIG-I/MAVS in the CNS Stimulates Production of Endogenous Type I IFN and Suppresses EAE
por: Kronborg Hansen, Anne K., et al.
Publicado: (2022)

Transplantation of human adipose-derived stem cells overexpressing LIF/IFN-β promotes recovery in experimental autoimmune encephalomyelitis (EAE)
por: Yousefi, Mahdieh, et al.
Publicado: (2022)

Adoptive transfer of EAE-like lesions from rats with coronavirus-induced demyelinating encephalomyelitis
por: Watanabe, Rihito, et al.
Publicado: (1983)

Thomas Rivers and the EAE model
por: Van Epps, Heather L.
Publicado: (2005)

Role of Microglia and Macrophages in Eae
por: Raivich, Gennadij, et al.
Publicado: (2005)

Bronchoalveolar Lavage Fluid IFN-γ (+) Th17 Cells and Regulatory T Cells in Pulmonary Sarcoidosis
por: Tøndell, Anders, et al.
Publicado: (2014)

Inflammatory activation of the FcγR and IFNγR pathways co-influences the differentiation and activity of osteoclasts
por: Groetsch, Bettina, et al.
Publicado: (2022)

Differential Anti-Tumor Effects of IFN-Inducible Chemokines CXCL9, CXCL10, and CXCL11 on a Mouse Squamous Cell Carcinoma Cell Line
por: Matsumoto, Ari, et al.
Publicado: (2023)

γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury
por: Sun, Guodong, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_3ktip792lm83v4eejd6f23j0mq