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PEGylated self-assembled enzyme-responsive nanoparticles for effective targeted therapy against lung tumors
BACKGROUND: Matrix-metalloproteinases, which are overexpressed in many types of cancer, can be applied to improve the bioavailability of chemotherapeutic drugs and guide therapeutic targeting. Thus, we aimed to develop enzyme-responsive nanoparticles based on a functionalized copolymer (mPEG-Peptide...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048871/ https://www.ncbi.nlm.nih.gov/pubmed/30012166 http://dx.doi.org/10.1186/s12951-018-0384-8 |