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Preventing false discovery of heterogeneous treatment effect subgroups in randomized trials

BACKGROUND: Heterogeneous treatment effects (HTEs), or systematic differences in treatment effectiveness among participants with different observable features, may be important when applying trial results to clinical practice. Current methods suffer from a potential for false detection of HTEs due t...

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Detalles Bibliográficos
Autores principales: Rigdon, Joseph, Baiocchi, Michael, Basu, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048878/
https://www.ncbi.nlm.nih.gov/pubmed/30012181
http://dx.doi.org/10.1186/s13063-018-2774-5