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Engineering of Escherichia coli for Krebs cycle-dependent production of malic acid
BACKGROUND: Malate is a C4-dicarboxylic acid widely used as an acidulant in the food and beverage industry. Rational engineering has been performed in the past for the development of microbial strains capable of efficient production of this metabolite. However, as malate can be a precursor for speci...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048880/ https://www.ncbi.nlm.nih.gov/pubmed/30012131 http://dx.doi.org/10.1186/s12934-018-0959-y |