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Severe hemophagocytic lymphohistiocytosis in a melanoma patient treated with ipilimumab + nivolumab

BACKGROUND: Treatment of metastatic melanoma patients with immune checkpoint inhibitors is an important standard of care. Side effects are due to immune activation, can affect virtually all organ systems, and are occasionally severe. Although hematologic toxicity has been reported, we present a case...

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Detalles Bibliográficos
Autores principales: Hantel, Andrew, Gabster, Brooke, Cheng, Jason X., Golomb, Harvey, Gajewski, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048909/
https://www.ncbi.nlm.nih.gov/pubmed/30012206
http://dx.doi.org/10.1186/s40425-018-0384-0