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Live-Cell Imaging of Chromatin Condensation Dynamics by CRISPR
The spatiotemporal organization of chromatin plays central roles in cellular function. The ribosomal DNA (rDNA) chromatin undergoes dynamic structural changes during mitosis and stress. Here, we developed a CRISPR-based imaging system and tracked the condensation dynamics of rDNA chromatin in live y...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048970/ https://www.ncbi.nlm.nih.gov/pubmed/30027155 http://dx.doi.org/10.1016/j.isci.2018.06.001 |