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Live-Cell Imaging of Chromatin Condensation Dynamics by CRISPR

The spatiotemporal organization of chromatin plays central roles in cellular function. The ribosomal DNA (rDNA) chromatin undergoes dynamic structural changes during mitosis and stress. Here, we developed a CRISPR-based imaging system and tracked the condensation dynamics of rDNA chromatin in live y...

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Detalles Bibliográficos
Autores principales:	Xue, Yuan, Acar, Murat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048970/ https://www.ncbi.nlm.nih.gov/pubmed/30027155 http://dx.doi.org/10.1016/j.isci.2018.06.001

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