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Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex
SF3b1 is an essential component of the U2 snRNP implicated in branch site (BS) recognition and found to be frequently mutated in several human cancers. While recent structures of yeast and human SF3b1 have revealed its molecular architecture, the importance of specific RNA:protein contacts and confo...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049509/ https://www.ncbi.nlm.nih.gov/pubmed/29752352 http://dx.doi.org/10.1261/rna.065664.118 |