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Nucleosomes around a mismatched base pair are excluded via an Msh2-dependent reaction with the aid of SNF2 family ATPase Smarcad1

Post-replicative correction of replication errors by the mismatch repair (MMR) system is critical for suppression of mutations. Although the MMR system may need to handle nucleosomes at the site of chromatin replication, how MMR occurs in the chromatin environment remains unclear. Here, we show that...

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Detalles Bibliográficos
Autores principales: Terui, Riki, Nagao, Koji, Kawasoe, Yoshitaka, Taki, Kanae, Higashi, Torahiko L., Tanaka, Seiji, Nakagawa, Takuro, Obuse, Chikashi, Masukata, Hisao, Takahashi, Tatsuro S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049510/
https://www.ncbi.nlm.nih.gov/pubmed/29899141
http://dx.doi.org/10.1101/gad.310995.117