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Polycystic kidney disease: a Hippo connection

Mutations in PKD1 and PKD2 are the leading cause of autosomal dominant polycystic kidney disease (ADPKD). In this issue of Genes & Development, a report by Cai and colleagues (pp. 781–793) reveals new insight into the molecular basis by which PKD1 deficiency leads to cystic kidney pathogenesis....

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Detalles Bibliográficos
Autores principales: Ma, Shenghong, Guan, Kun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049516/
https://www.ncbi.nlm.nih.gov/pubmed/29921661
http://dx.doi.org/10.1101/gad.316570.118