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Total chemical synthesis and biophysical properties of a designed soluble 24 kDa amyloid analogue
Discovering molecular probes that specifically recognize distinct amyloid structures is highly important for physiological studies of protein-misfolding diseases as well as for the development of diagnostic reagents and inhibitors of amyloid self-assembly. Here, we demonstrate an approach that allow...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049524/ https://www.ncbi.nlm.nih.gov/pubmed/30061991 http://dx.doi.org/10.1039/c8sc01790e |