Site-selective C–C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations

The bioconjugation of proteins with small molecules has proved an invaluable strategy for probing and perturbing biological mechanisms. The general use of chemical methods for protein functionalisation can be limited however by the requirement for complicated reaction partners to be present in large...

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Detalles Bibliográficos
Autores principales: Spears, Richard J., Brabham, Robin L., Budhadev, Darshita, Keenan, Tessa, McKenna, Sophie, Walton, Julia, Brannigan, James. A., Brzozowski, A. Marek, Wilkinson, Anthony J., Plevin, Michael, Fascione, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049525/
https://www.ncbi.nlm.nih.gov/pubmed/30061990
http://dx.doi.org/10.1039/c8sc01617h

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049525/
https://www.ncbi.nlm.nih.gov/pubmed/30061990
http://dx.doi.org/10.1039/c8sc01617h

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