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Site-selective C–C modification of proteins at neutral pH using organocatalyst-mediated cross aldol ligations
The bioconjugation of proteins with small molecules has proved an invaluable strategy for probing and perturbing biological mechanisms. The general use of chemical methods for protein functionalisation can be limited however by the requirement for complicated reaction partners to be present in large...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Royal Society of Chemistry
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049525/ https://www.ncbi.nlm.nih.gov/pubmed/30061990 http://dx.doi.org/10.1039/c8sc01617h |