Defective Synapse Maturation and Enhanced Synaptic Plasticity in Shank2 Δex7(–/–) Mice

Autism spectrum disorders (ASDs) are neurodevelopmental disorders with a strong genetic etiology. Since mutations in human SHANK genes have been found in patients with autism, genetic mouse models are used for a mechanistic understanding of ASDs and the development of therapeutic strategies. SHANKs...

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Detalles Bibliográficos
Autores principales: Wegener, Stephanie, Buschler, Arne, Stempel, A. Vanessa, Kang, Sukjae J., Lim, Chae-Seok, Kaang, Bong-Kiun, Shoichet, Sarah A., Manahan-Vaughan, Denise, Schmitz, Dietmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049608/
https://www.ncbi.nlm.nih.gov/pubmed/30023428
http://dx.doi.org/10.1523/ENEURO.0398-17.2018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049608/
https://www.ncbi.nlm.nih.gov/pubmed/30023428
http://dx.doi.org/10.1523/ENEURO.0398-17.2018

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