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CAD/POLD2 gene expression is associated with poor overall survival and chemoresistance in bladder urothelial carcinoma

Somatic mutations in DNA repair genes have been clinically associated with chemosensitivity, although few studies have interrogated the nucleotide synthesis pathways that supply DNA repair processes. Previous work suggests that bladder urothelial carcinoma is uniquely enriched for mutations in nucle...

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Detalles Bibliográficos
Autores principales: Givechian, Kevin B., Garner, Chad, Garban, Hermes, Rabizadeh, Shahrooz, Soon-Shiong, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049856/
https://www.ncbi.nlm.nih.gov/pubmed/30038717
http://dx.doi.org/10.18632/oncotarget.25701