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Detection of cooperatively bound transcription factor pairs using ChIP-seq peak intensities and expectation maximization
Transcription factors (TFs) often work cooperatively, where the binding of one TF to DNA enhances the binding affinity of a second TF to a nearby location. Such cooperative binding is important for activating gene expression from promoters and enhancers in both prokaryotic and eukaryotic cells. Exis...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049898/ https://www.ncbi.nlm.nih.gov/pubmed/30016330 http://dx.doi.org/10.1371/journal.pone.0199771 |