Inference of cell type content from human brain transcriptomic datasets illuminates the effects of age, manner of death, dissection, and psychiatric diagnosis

Psychiatric illness is unlikely to arise from pathology occurring uniformly across all cell types in affected brain regions. Despite this, transcriptomic analyses of the human brain have typically been conducted using macro-dissected tissue due to the difficulty of performing single-cell type analys...

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Detalles Bibliográficos
Autores principales: Hagenauer, Megan Hastings, Schulmann, Anton, Li, Jun Z., Vawter, Marquis P., Walsh, David M., Thompson, Robert C., Turner, Cortney A., Bunney, William E., Myers, Richard M., Barchas, Jack D., Schatzberg, Alan F., Watson, Stanley J., Akil, Huda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049916/
https://www.ncbi.nlm.nih.gov/pubmed/30016334
http://dx.doi.org/10.1371/journal.pone.0200003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049916/
https://www.ncbi.nlm.nih.gov/pubmed/30016334
http://dx.doi.org/10.1371/journal.pone.0200003

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