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Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

Eliciting broadly neutralizing antibodies (bnAbs) targeting envelope (Env) is a major goal of HIV vaccine development, but cross-clade breadth from immunization has only sporadically been observed. Recently, Xu et al (2018) elicited cross-reactive neutralizing antibody responses in a variety of anim...

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Detalles Bibliográficos
Autores principales: Dingens, Adam S., Acharya, Priyamvada, Haddox, Hugh K., Rawi, Reda, Xu, Kai, Chuang, Gwo-Yu, Wei, Hui, Zhang, Baoshan, Mascola, John R., Carragher, Bridget, Potter, Clinton S., Overbaugh, Julie, Kwong, Peter D., Bloom, Jesse D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049957/
https://www.ncbi.nlm.nih.gov/pubmed/29975771
http://dx.doi.org/10.1371/journal.ppat.1007159