Cargando…

Dual roles for ATP in the regulation of phase separated protein aggregates in Xenopus oocyte nucleoli

For many proteins, aggregation is one part of a structural equilibrium that can occur. Balancing productive aggregation versus pathogenic aggregation that leads to toxicity is critical and known to involve adenosine triphosphate (ATP) dependent action of chaperones and disaggregases. Recently a seco...

Descripción completa

Detalles Bibliográficos
Autores principales: Hayes, Michael H, Peuchen, Elizabeth H, Dovichi, Norman J, Weeks, Daniel L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050040/
https://www.ncbi.nlm.nih.gov/pubmed/30015615
http://dx.doi.org/10.7554/eLife.35224