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Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes

Retinal ganglion cells (RGCs) convey the major output of information collected from the eye to the brain. Thirty subtypes of RGCs have been identified to date. Here, we analyze 6225 RGCs (average of 5000 genes per cell) from right and left eyes by single-cell RNA-seq and classify them into 40 subtyp...

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Detalles Bibliográficos
Autores principales: Rheaume, Bruce A., Jereen, Amyeo, Bolisetty, Mohan, Sajid, Muhammad S., Yang, Yue, Renna, Kathleen, Sun, Lili, Robson, Paul, Trakhtenberg, Ephraim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050223/
https://www.ncbi.nlm.nih.gov/pubmed/30018341
http://dx.doi.org/10.1038/s41467-018-05134-3