Cargando…

Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes

Retinal ganglion cells (RGCs) convey the major output of information collected from the eye to the brain. Thirty subtypes of RGCs have been identified to date. Here, we analyze 6225 RGCs (average of 5000 genes per cell) from right and left eyes by single-cell RNA-seq and classify them into 40 subtyp...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rheaume, Bruce A., Jereen, Amyeo, Bolisetty, Mohan, Sajid, Muhammad S., Yang, Yue, Renna, Kathleen, Sun, Lili, Robson, Paul, Trakhtenberg, Ephraim F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050223/ https://www.ncbi.nlm.nih.gov/pubmed/30018341 http://dx.doi.org/10.1038/s41467-018-05134-3

Ejemplares similares

Author Correction: Single cell transcriptome profiling of retinal ganglion cells identifies cellular subtypes
por: Rheaume, Bruce A., et al.
Publicado: (2018)

Transcriptomic profiling of retinal cells reveals a subpopulation of microglia/macrophages expressing Rbpms and Spp1 markers of retinal ganglion cells (RGCs) that confound identification of RGCs
por: Theune, William C., et al.
Publicado: (2023)

Pten inhibition dedifferentiates long-distance axon-regenerating intrinsically photosensitive retinal ganglion cells and upregulates mitochondria-associated Dynlt1a and Lars2
por: Rheaume, Bruce A., et al.
Publicado: (2023)

Corneal nonmyelinating Schwann cells illuminated by single‐cell transcriptomics and visualized by protein biomarkers
por: Bargagna‐Mohan, Paola, et al.
Publicado: (2020)

Post-injury born oligodendrocytes incorporate into the glial scar and contribute to the inhibition of axon regeneration
por: Xing, Jian, et al.
Publicado: (2023)

Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation
por: Paknahad, Javad, et al.
Publicado: (2021)

β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival
por: Santos, Andrea Rachelle C., et al.
Publicado: (2012)

Publisher Correction: Color and cellular selectivity of retinal ganglion cell subtypes through frequency modulation of electrical stimulation
por: Paknahad, Javad, et al.
Publicado: (2021)

Continuation Rates of the Etonogestrel Implant and Factors Associated With Early Discontinuation
por: Hines, Genesis, et al.
Publicado: (2023)

Mapping developmental trajectories and subtype diversity of normal and glaucomatous human retinal ganglion cells by single‐cell transcriptome analysis
por: Teotia, Pooja, et al.
Publicado: (2020)

Subtype-specific response of retinal ganglion cells to optic nerve crush
por: Daniel, S., et al.
Publicado: (2018)

Subtype-specific survival and regeneration of retinal ganglion cells in response to injury
por: Tapia, Mary L., et al.
Publicado: (2022)

Retinal patterns and the cellular repertoire of neuropsin (Opn5) retinal ganglion cells
por: D'Souza, Shane P., et al.
Publicado: (2021)

The extent of extra-axonal tissue damage determines the levels of CSPG upregulation and the success of experimental axon regeneration in the CNS
por: Kim, Juhwan, et al.
Publicado: (2018)

Retinal Ganglion Cell Diversity and Subtype Specification from Human Pluripotent Stem Cells
por: Langer, Kirstin B., et al.
Publicado: (2018)

945. Prevalence of HIV Associated Non-AIDS Conditions and Associated Risk Factors among Hospitalized HIV-infected Patients in India
por: Jereen, Amyeo A, et al.
Publicado: (2020)

Developmentally upregulated transcriptional elongation factor a like 3 suppresses axon regeneration after optic nerve injury
por: Lukomska, Agnieszka, et al.
Publicado: (2021)

Single-cell transcriptomes identify human islet cell signatures and reveal cell-type–specific expression changes in type 2 diabetes
por: Lawlor, Nathan, et al.
Publicado: (2017)

Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease
por: VanderWall, Kirstin B., et al.
Publicado: (2020)

Selective Activation of Retinal Ganglion Cell Subtypes Through Targeted Electrical Stimulation Parameters
por: Paknahad, Javad, et al.
Publicado: (2022)

Cellular properties of intrinsically photosensitive retinal ganglion cells during postnatal development
por: Lucas, Jasmine A., et al.
Publicado: (2019)

Phototransduction in Retinal Ganglion Cells
por: Detwiler, Peter B.
Publicado: (2018)

In vitro Methods to Cultivate Spiral Ganglion Cells, and Purification of Cellular Subtypes for Induced Neuronal Reprogramming
por: Meas, Steven J., et al.
Publicado: (2018)

Cellular Origin of Spontaneous Ganglion Cell Spike Activity in Animal Models of Retinitis Pigmentosa
por: Margolis, David J., et al.
Publicado: (2011)

Comparative Proteomic Study of Retinal Ganglion Cells Undergoing Various Types of Cellular Stressors
por: Starr, Christopher R., et al.
Publicado: (2023)

Premature axon-oligodendrocyte interaction contributes to stalling of experimental axon regeneration after injury to the white matter
por: Trakhtenberg, Ephraim F.
Publicado: (2023)

The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina
por: Groman-Lupa, Sergio, et al.
Publicado: (2017)

A melanopsin ganglion cell subtype forms a dorsal retinal mosaic projecting to the supraoptic nucleus
por: Berry, Michael H., et al.
Publicado: (2023)

On the Generation and Regeneration of Retinal Ganglion Cells
por: Oliveira-Valença, Viviane M., et al.
Publicado: (2020)

Molecular Biology of Retinal Ganglion Cells
por: Völgyi, Béla
Publicado: (2020)

Neurogenesis and Specification of Retinal Ganglion Cells
por: Nguyen-Ba-Charvet, Kim Tuyen, et al.
Publicado: (2020)

The pattern of retinal ganglion cell dysfunction in Leber hereditary optic neuropathy
por: Majander, A., et al.
Publicado: (2017)

Modeling extracellular stimulation of retinal ganglion cells: theoretical and practical aspects
por: Kish, Kathleen E, et al.
Publicado: (2023)

Agmatine protects retinal ganglion cells from hypoxia-induced apoptosis in transformed rat retinal ganglion cell line
por: Hong, Samin, et al.
Publicado: (2007)

Single-Cell RNA Sequencing Reveals Molecular Features of Heterogeneity in the Murine Retinal Pigment Epithelium
por: Pandey, Ravi S., et al.
Publicado: (2022)

Retinal Ganglion Cells are Resistant to Photoreceptor Loss in Retinal Degeneration
por: Lin, Bin, et al.
Publicado: (2013)

Transcriptomic profiles of retinal ganglion cells are defined by the magnitude of intraocular pressure elevation in adult mice
por: Park, Yong H., et al.
Publicado: (2019)

Stem cell therapy for retinal ganglion cell degeneration
por: Cen, Ling-Ping, et al.
Publicado: (2018)

Polarization and orientation of retinal ganglion cells in vivo
por: Zolessi, Flavio R, et al.
Publicado: (2006)

Hypoxia-ischemia and retinal ganglion cell damage
por: Kaur, Charanjit, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_0slg0idg60gql9tsn5c4ktg34m