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The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

Cell cycle progression in mammals is modulated by two ubiquitin ligase complexes, CRL4 and SCF, which facilitate degradation of chromatin substrates involved in the regulation of DNA replication. One member of the CRL4 complex, the WD-40 containing protein RepID (DCAF14/PHIP), selectively binds and...

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Detalles Bibliográficos
Autores principales: Jang, Sang-Min, Zhang, Ya, Utani, Koichi, Fu, Haiqing, Redon, Christophe E., Marks, Anna B., Smith, Owen K., Redmond, Catherine J., Baris, Adrian M., Tulchinsky, Danielle A., Aladjem, Mirit I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050238/
https://www.ncbi.nlm.nih.gov/pubmed/30018425
http://dx.doi.org/10.1038/s41467-018-05177-6