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A monocyte gene expression signature in the early clinical course of Parkinson’s disease

Microglia are the main immune cells of the brain and express a large genetic pattern of genes linked to Parkinson’s disease risk alleles. Monocytes like microglia are myeloid-lineage cells, raising the questions of the extent to which they share gene expression with microglia and whether they are al...

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Detalles Bibliográficos
Autores principales: Schlachetzki, Johannes C. M., Prots, Iryna, Tao, Jenhan, Chun, Hyun B., Saijo, Kaoru, Gosselin, David, Winner, Beate, Glass, Christopher K., Winkler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050266/
https://www.ncbi.nlm.nih.gov/pubmed/30018301
http://dx.doi.org/10.1038/s41598-018-28986-7