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APC2 controls dendrite development by promoting microtubule dynamics

Mixed polarity microtubule organization is the signature characteristic of vertebrate dendrites. Oppositely oriented microtubules form the basis for selective cargo trafficking in neurons, however the mechanisms that establish and maintain this organization are unclear. Here, we show that APC2, the...

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Detalles Bibliográficos
Autores principales: Kahn, Olga I., Schätzle, Philipp, van de Willige, Dieudonnée, Tas, Roderick P., Lindhout, Feline W., Portegies, Sybren, Kapitein, Lukas C., Hoogenraad, Casper C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050278/
https://www.ncbi.nlm.nih.gov/pubmed/30018294
http://dx.doi.org/10.1038/s41467-018-05124-5