A potentially abundant junctional RNA motif stabilized by m(6)A and Mg(2+)

N(6)-Methyladenosine (m(6)A) is an abundant post-transcriptional RNA modification that influences multiple aspects of gene expression. In addition to recruiting proteins, m(6)A can modulate RNA function by destabilizing base pairing. Here, we show that when neighbored by a 5ʹ bulge, m(6)A stabilizes...

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Detalles Bibliográficos
Autores principales: Liu, Bei, Merriman, Dawn K., Choi, Seung H., Schumacher, Maria A., Plangger, Raphael, Kreutz, Christoph, Horner, Stacy M., Meyer, Kate D., Al-Hashimi, Hashim M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050335/
https://www.ncbi.nlm.nih.gov/pubmed/30018356
http://dx.doi.org/10.1038/s41467-018-05243-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050335/
https://www.ncbi.nlm.nih.gov/pubmed/30018356
http://dx.doi.org/10.1038/s41467-018-05243-z

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