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A potentially abundant junctional RNA motif stabilized by m(6)A and Mg(2+)
N(6)-Methyladenosine (m(6)A) is an abundant post-transcriptional RNA modification that influences multiple aspects of gene expression. In addition to recruiting proteins, m(6)A can modulate RNA function by destabilizing base pairing. Here, we show that when neighbored by a 5ʹ bulge, m(6)A stabilizes...
Autores principales: | Liu, Bei, Merriman, Dawn K., Choi, Seung H., Schumacher, Maria A., Plangger, Raphael, Kreutz, Christoph, Horner, Stacy M., Meyer, Kate D., Al-Hashimi, Hashim M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050335/ https://www.ncbi.nlm.nih.gov/pubmed/30018356 http://dx.doi.org/10.1038/s41467-018-05243-z |
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