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IRF5 Is a Key Regulator of Macrophage Response to Lipopolysaccharide in Newborns

Infections are a leading cause of mortality and morbidity in newborns. The high susceptibility of newborns to infection has been associated with a limited capacity to mount protective immune responses. Monocytes and macrophages are involved in the initiation, amplification, and termination of immune...

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Detalles Bibliográficos
Autores principales: Schneider, Anina, Weier, Manuela, Herderschee, Jacobus, Perreau, Matthieu, Calandra, Thierry, Roger, Thierry, Giannoni, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050365/
https://www.ncbi.nlm.nih.gov/pubmed/30050534
http://dx.doi.org/10.3389/fimmu.2018.01597