F(1)F(0)-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation

F(1)F(0)-ATP synthase inhibitory factor 1 (IF1) inhibits the reverse mode of F(1)F(0)-ATP synthase, and therefore protects cellular ATP content at the expense of accelerated loss of mitochondrial membrane potential (ΔΨm). There is considerable variability in IF1 expression and its influence on bioen...

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Detalles Bibliográficos
Autores principales: Tanton, Helen, Voronina, Svetlana, Evans, Anthony, Armstrong, Jane, Sutton, Robert, Criddle, David N., Haynes, Lee, Schmid, Michael C., Campbell, Fiona, Costello, Eithne, Tepikin, Alexei V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050379/
https://www.ncbi.nlm.nih.gov/pubmed/30050450
http://dx.doi.org/10.3389/fphys.2018.00833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050379/
https://www.ncbi.nlm.nih.gov/pubmed/30050450
http://dx.doi.org/10.3389/fphys.2018.00833

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