Cargando…

F(1)F(0)-ATP Synthase Inhibitory Factor 1 in the Normal Pancreas and in Pancreatic Ductal Adenocarcinoma: Effects on Bioenergetics, Invasion and Proliferation

F(1)F(0)-ATP synthase inhibitory factor 1 (IF1) inhibits the reverse mode of F(1)F(0)-ATP synthase, and therefore protects cellular ATP content at the expense of accelerated loss of mitochondrial membrane potential (ΔΨm). There is considerable variability in IF1 expression and its influence on bioen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanton, Helen, Voronina, Svetlana, Evans, Anthony, Armstrong, Jane, Sutton, Robert, Criddle, David N., Haynes, Lee, Schmid, Michael C., Campbell, Fiona, Costello, Eithne, Tepikin, Alexei V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050379/ https://www.ncbi.nlm.nih.gov/pubmed/30050450 http://dx.doi.org/10.3389/fphys.2018.00833

Ejemplares similares

Altered Bioenergetics of Blood Cell Sub-Populations in Acute Pancreatitis Patients
por: Morton, Jack C., et al.
Publicado: (2019)

Mitochondrial Targeting of Antioxidants Alters Pancreatic Acinar Cell Bioenergetics and Determines Cell Fate
por: Armstrong, Jane A., et al.
Publicado: (2019)

Phosphorus Chemistry at the Roots of Bioenergetics: Ligand Permutation as the Molecular Basis of the Mechanism of ATP Synthesis/Hydrolysis by F(O)F(1)-ATP Synthase
por: Nath, Sunil
Publicado: (2023)

cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: Effects of PKA and EPAC()
por: Burdyga, Alex, et al.
Publicado: (2013)

Evolution of the F(0)F(1) ATP Synthase Complex in Light of the Patchy Distribution of Different Bioenergetic Pathways across Prokaryotes
por: Koumandou, Vassiliki Lila, et al.
Publicado: (2014)

Bioenergetic consequences of F(o)F(1)–ATP synthase/ATPase deficiency in two life cycle stages of Trypanosoma brucei
por: Hierro-Yap, Carolina, et al.
Publicado: (2021)

Rotary catalysis of F(o)F(1)-ATP synthase
por: Watanabe, Rikiya
Publicado: (2013)

Efficient ATP synthesis by thermophilic Bacillus F(o)F(1)-ATP synthase
por: Soga, Naoki, et al.
Publicado: (2011)

F(1)F(O) ATP synthase molecular motor mechanisms
por: Frasch, Wayne D., et al.
Publicado: (2022)

Knockout of the Mitochondrial Calcium Uniporter Strongly Suppresses Stimulus-Metabolism Coupling in Pancreatic Acinar Cells but Does not Reduce Severity of Experimental Acute Pancreatitis
por: Chvanov, Michael, et al.
Publicado: (2020)

Oxidative stress alters mitochondrial bioenergetics and modifies pancreatic cell death independently of cyclophilin D, resulting in an apoptosis-to-necrosis shift
por: Armstrong, Jane A., et al.
Publicado: (2018)

Unusual features of the c-ring of F(1)F(O) ATP synthases
por: Vlasov, A. V., et al.
Publicado: (2019)

ATP synthase: from single molecule to human bioenergetics
por: KAGAWA, Yasuo
Publicado: (2010)

ATP Synthase and Mitochondrial Bioenergetics Dysfunction in Alzheimer’s Disease
por: Patro, Somya, et al.
Publicado: (2021)

ATP depletion induces translocation of STIM1 to puncta and formation of STIM1–ORAI1 clusters: translocation and re-translocation of STIM1 does not require ATP
por: Chvanov, Michael, et al.
Publicado: (2008)

Metabolic Trade-offs in Yeast are Caused by F1F0-ATP synthase
por: Nilsson, Avlant, et al.
Publicado: (2016)

A mitochondrial megachannel resides in monomeric F(1)F(O) ATP synthase
por: Mnatsakanyan, Nelli, et al.
Publicado: (2019)

The mitochondrial Hsp70 controls the assembly of the F(1)F(O)-ATP synthase
por: Song, Jiyao, et al.
Publicado: (2023)

F(1)·F(o) ATP Synthase/ATPase: Contemporary View on Unidirectional Catalysis
por: Zharova, Tatyana V., et al.
Publicado: (2023)

INA complex liaises the F(1)F(o)-ATP synthase membrane motor modules
por: Naumenko, Nataliia, et al.
Publicado: (2017)

Reversible optical control of F(1)F(o)‐ATP synthase using photoswitchable inhibitors
por: Eisel, Bianca, et al.
Publicado: (2018)

Inorganic polyphosphate is produced and hydrolyzed in F(0)F(1)-ATP synthase of mammalian mitochondria
por: Baev, Artyom Y., et al.
Publicado: (2020)

The δ subunit of F(1)F(o)-ATP synthase is required for pathogenicity of Candida albicans
por: Li, Shuixiu, et al.
Publicado: (2021)

Intracellular rupture, exocytosis and actin interaction of endocytic vacuoles in pancreatic acinar cells: initiating events in acute pancreatitis
por: Chvanov, Michael, et al.
Publicado: (2018)

Possible Involvement of F1F0-ATP synthase and Intracellular ATP in Keratinocyte Differentiation in normal skin and skin lesions
por: Xiaoyun, Xie, et al.
Publicado: (2017)

Changes within the central stalk of E. coli F(1)F(o) ATP synthase observed after addition of ATP
por: Sobti, Meghna, et al.
Publicado: (2023)

Mechanism of ADP-Inhibited ATP Hydrolysis in Single Proton-Pumping F(o)F(1)-ATP Synthase Trapped in Solution
por: Pérez, Iván, et al.
Publicado: (2023)

A New Type of Proton Coordination in an F(1)F(o)-ATP Synthase Rotor Ring
por: Preiss, Laura, et al.
Publicado: (2010)

An alternative role of F(o)F(1)-ATP synthase in Escherichia coli: synthesis of thiamine triphosphate
por: Gigliobianco, Tiziana, et al.
Publicado: (2013)

Visualizing Mitochondrial F(o)F(1)-ATP Synthase as the Target of the Immunomodulatory Drug Bz-423
por: Starke, Ilka, et al.
Publicado: (2018)

Nonequilibrium fluctuations of lipid membranes by the rotating motor protein F(1)F(0)-ATP synthase
por: Almendro-Vedia, Víctor G., et al.
Publicado: (2017)

HtrA2 deficiency causes mitochondrial uncoupling through the F(1)F(0)-ATP synthase and consequent ATP depletion
por: Plun-Favreau, H, et al.
Publicado: (2012)

F-Type ATP Synthase Assembly Factors Atp11 and Atp12 in Arabidopsis
por: Duan, Zhikun, et al.
Publicado: (2020)

The mitochondrial chaperone TRAP1 regulates F-ATP synthase channel formation
por: Cannino, Giuseppe, et al.
Publicado: (2022)

Autophagy, Acute Pancreatitis and the Metamorphoses of a Trypsinogen-Activating Organelle
por: Voronina, Svetlana, et al.
Publicado: (2022)

Saltatory formation, sliding and dissolution of ER–PM junctions in migrating cancer cells
por: Dingsdale, Hayley, et al.
Publicado: (2013)

Biology, role and therapeutic potential of circulating histones in acute inflammatory disorders
por: Szatmary, Peter, et al.
Publicado: (2018)

The F(0)F(1)-ATP Synthase Complex Contains Novel Subunits and Is Essential for Procyclic Trypanosoma brucei
por: Zíková, Alena, et al.
Publicado: (2009)

Correction: A New Type of Proton Coordination in an F(1)F(o)-ATP Synthase Rotor Ring
por: Preiss, Laura, et al.
Publicado: (2010)

Correction: A New Type of Proton Coordination in an F(1)F(o)-ATP Synthase Rotor Ring
por: Preiss, Laura, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qril210l2vc3rehmgc6qje2f6d