Pharmacological Inhibition of Indoleamine 2,3-Dioxygenase-2 and Kynurenine 3-Monooxygenase, Enzymes of the Kynurenine Pathway, Significantly Diminishes Neuropathic Pain in a Rat Model

Neuropathic pain caused by a primary injury or dysfunction in the peripheral or central nervous system is a tremendous therapeutic challenge. Here, we have collected the first evidence from a single study on the potential contributions to neuropathic pain development by enzymes in the kynurenine pat...

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Detalles Bibliográficos
Autores principales: Rojewska, Ewelina, Ciapała, Katarzyna, Piotrowska, Anna, Makuch, Wioletta, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050382/
https://www.ncbi.nlm.nih.gov/pubmed/30050435
http://dx.doi.org/10.3389/fphar.2018.00724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050382/
https://www.ncbi.nlm.nih.gov/pubmed/30050435
http://dx.doi.org/10.3389/fphar.2018.00724

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