Valproic Acid Induces Endothelial-to-Mesenchymal Transition-Like Phenotypic Switching

Valproic acid (VPA), a histone deacetylase (HDAC) inhibitor, is a widely used anticonvulsant drug that is currently undergoing clinical evaluation for anticancer therapy due to its anti-angiogenic potential. Endothelial cells (ECs) can transition into mesenchymal cells and this form of EC plasticity...

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Detalles Bibliográficos
Autores principales: Murugavel, Shamini, Bugyei-Twum, Antoinette, Matkar, Pratiek N., Al-Mubarak, Husain, Chen, Hao H., Adam, Mohamed, Jain, Shubha, Narang, Tanya, Abdin, Rawand M., Qadura, Mohammad, Connelly, Kim A., Leong-Poi, Howard, Singh, Krishna K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050396/
https://www.ncbi.nlm.nih.gov/pubmed/30050438
http://dx.doi.org/10.3389/fphar.2018.00737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050396/
https://www.ncbi.nlm.nih.gov/pubmed/30050438
http://dx.doi.org/10.3389/fphar.2018.00737

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