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Characterizing Glioblastoma Heterogeneity via Single-Cell Receptor Quantification

Dysregulation of tyrosine kinase receptor (RTK) signaling pathways play important roles in glioblastoma (GBM). However, therapies targeting these signaling pathways have not been successful, partially because of drug resistance. Increasing evidence suggests that tumor heterogeneity, more specificall...

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Detalles Bibliográficos
Autores principales: Chen, Si, Le, Thien, Harley, Brendan A. C., Imoukhuede, P. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050407/
https://www.ncbi.nlm.nih.gov/pubmed/30050899
http://dx.doi.org/10.3389/fbioe.2018.00092