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Leucine-rich G Protein-coupled Receptor-5 Is Significantly Increased in the Aqueous Humor of Human Eye with Proliferative Diabetic Retinopathy

Leucine-rich G protein-coupled receptor-5 (LGR5) is known to be a stem cell marker in many organs. LGR5 may have important roles in proliferative diabetic retinopathy (PDR) because LGR5 potentiate the Wnt/β-catenin pathway, which plays crucial roles in pathologic neovascularization in the retina. Th...

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Detalles Bibliográficos
Autores principales: Hong, Eun Hee, Hwang, Mina, Shin, Yong Un, Park, Hyun-Hee, Koh, Seong-Ho, Cho, Heeyoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050418/
https://www.ncbi.nlm.nih.gov/pubmed/30022875
http://dx.doi.org/10.5607/en.2018.27.3.238