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Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets

Alzheimer's disease (AD) is characterized by an accumulation of β-amyloid (Aβ(42)) accompanied by brain atrophy and cognitive decline. Several recent studies have shown that Aβ(42) accumulation is associated with gray matter (GM) changes prior to the development of cognitive impairment, in the...

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Detalles Bibliográficos
Autores principales: Falcon, Carles, Tucholka, Alan, Monté-Rubio, Gemma C., Cacciaglia, Raffaele, Operto, Grégory, Rami, Lorena, Gispert, Juan Domingo, Molinuevo, José Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050455/
https://www.ncbi.nlm.nih.gov/pubmed/30023169
http://dx.doi.org/10.1016/j.nicl.2018.04.016