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Longitudinal structural cerebral changes related to core CSF biomarkers in preclinical Alzheimer's disease: A study of two independent datasets
Alzheimer's disease (AD) is characterized by an accumulation of β-amyloid (Aβ(42)) accompanied by brain atrophy and cognitive decline. Several recent studies have shown that Aβ(42) accumulation is associated with gray matter (GM) changes prior to the development of cognitive impairment, in the...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050455/ https://www.ncbi.nlm.nih.gov/pubmed/30023169 http://dx.doi.org/10.1016/j.nicl.2018.04.016 |