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Impact of partial volume correction on the regional correspondence between in vivo [C-11]PiB PET and postmortem measures of Aβ load

The positron emission tomography (PET) radiotracer Pittsburgh Compound B ([C-11]PiB) demonstrates a high affinity for fibrillary amyloid-beta (Aβ) aggregates. However, [C-11]PiB's in vivo sensitivity and specificity is an ongoing area of investigation in correlation studies with postmortem meas...

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Detalles Bibliográficos
Autores principales: Minhas, Davneet S., Price, Julie C., Laymon, Charles M., Becker, Carl R., Klunk, William E., Tudorascu, Dana L., Abrahamson, Eric E., Hamilton, Ronald L., Kofler, Julia K., Mathis, Chester A., Lopez, Oscar L., Ikonomovic, Milos D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050460/
https://www.ncbi.nlm.nih.gov/pubmed/30023168
http://dx.doi.org/10.1016/j.nicl.2018.04.007