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miR‐21 promotes cardiac fibroblast‐to‐myofibroblast transformation and myocardial fibrosis by targeting Jagged1

Myocardial fibrosis after myocardial infarction (MI) is a leading cause of heart diseases. MI activates cardiac fibroblasts (CFs) and promotes CF to myofibroblast transformation (CMT). This study aimed to investigate the role of miR‐21 in the regulation of CMT and myocardial fibrosis. Primary rat CF...

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Detalles Bibliográficos
Autores principales: Zhou, Xue‐liang, Xu, Hua, Liu, Zhi‐bo, Wu, Qi‐cai, Zhu, Rong‐rong, Liu, Ji‐chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050485/
https://www.ncbi.nlm.nih.gov/pubmed/29808534
http://dx.doi.org/10.1111/jcmm.13654