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Methylation‐reprogrammed Wnt/β‐catenin signalling mediated prenatal hypoxia‐induced brain injury in foetal and offspring rats

Prenatal hypoxia (PH) is a common pregnancy complication, harmful to brain development. This study investigated whether and how PH affected Wnt pathway in the brain. Pregnant rats were exposed to hypoxia (10.5% O(2)) or normoxia (21% O(2); Control). Foetal brain weight and body weight were decreased...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Zhang, Mengshu, Li, Lingjun, Wei, Bin, He, Axin, Lu, Likui, Li, Xiang, Zhang, Lubo, Xu, Zhice, Sun, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050486/
https://www.ncbi.nlm.nih.gov/pubmed/29808608
http://dx.doi.org/10.1111/jcmm.13660