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MiR‐149 sensitizes esophageal cancer cell lines to cisplatin by targeting DNA polymerase β

Human DNA polymerase β (polβ) is a small, monomeric protein essential for short‐patch base excision repair (BER). polβ plays an important role in the regulation of chemotherapy sensitivity in tumour cells. In this study, we determined that the expression levels of polβ mRNA and miR‐149 in tumour tis...

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Detalles Bibliográficos
Autores principales: Wang, Yuanyuan, Chen, Jiahui, Zhang, Man, Zhang, Wenwen, Li, Min, Zang, Wenqiao, Dong, Ziming, Zhao, Guoqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050494/
https://www.ncbi.nlm.nih.gov/pubmed/29726631
http://dx.doi.org/10.1111/jcmm.13659