Cargando…

Aldehyde dehydrogenase 2 activation ameliorates CCl(4)‐induced chronic liver fibrosis in mice by up‐regulating Nrf2/HO‐1 antioxidant pathway

Mitochondrial aldehyde dehydrogenase 2 (ALDH2) is critical in the pathogenesis of alcoholic liver cirrhosis. However, the effect of ALHD2 on liver fibrosis remains to be further elucidated. This study aimed to demonstrate whether ALDH2 regulates carbon tetrachloride (CCl(4))‐induced liver fibrosis a...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Xin, Luo, Qin, Zhu, Hong, Liu, Xuejing, Dong, Zhen, Zhang, Kaili, Zou, Yunzeng, Wu, Jian, Ge, Junbo, Sun, Aijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050510/
https://www.ncbi.nlm.nih.gov/pubmed/29799157
http://dx.doi.org/10.1111/jcmm.13677