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Long-chain fatty acid activates hepatocytes through CD36 mediated oxidative stress

BACKGROUND: Accumulating evidence suggests that activated hepatocytes are involved in the deposition of the excess extracellular matrix during liver fibrosis via the epithelial to mesenchymal transition. Lipid accumulation in hepatocytes are implicated in the pathogenesis of chronic liver injury. CD...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Yang, Ping, Zuo, Guoqing, He, Song, Tan, Wei, Zhang, Xiaoyu, Su, Chunxiao, Zhao, Lei, Wei, Li, Chen, Yao, Ruan, Xiongzhong, Chen, Yaxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050651/
https://www.ncbi.nlm.nih.gov/pubmed/30016988
http://dx.doi.org/10.1186/s12944-018-0790-9